Methylene Blue & Mitochondria: How This Compound Fights Alzheimer's and Brain Aging

02 Apr 2025 • 61 min • EN
61 min
00:00
01:01:39
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I"m excited to share my conversation with Dr. Scott Sherr, where we dive deep into methylene blue - a compound you"ve probably seen all over social media lately (those blue tongues!). As someone whose primary research focuses on Alzheimer"s disease, I was fascinated to explore the science behind this molecule that dates back to the 1870s and was actually the first drug registered with the FDA in 1897.   The most fascinating insight for me was learning how methylene blue can serve as an electron acceptor in our mitochondria - essentially functioning as a substitute for oxygen when our cells are under stress. This explains why it shows promise for everything from traumatic brain injury to cognitive enhancement and even as a potential alternative to stimulant medications.    If you"re interested in optimizing brain performance, understanding mitochondrial health, or simply curious about this blue compound that"s suddenly everywhere, this episode provides both the scientific foundation and practical applications you need.   Subscribe to The Neuroscience Experience for more conversations at the intersection of brain science and performance. I"m committed to bringing you evidence-based insights that you can apply to your own health journey.  Sponsors A huge thank you to my sponsors for supporting this episode. Check them out and enjoy exclusive discounts: Hone Health – Take control of your hormones with at-home testing designed specifically for men. Get personalized insights and expert guidance to optimize your health and performance. Learn more at: https://honehealth.com/ Momentous – Science-backed supplements trusted by elite athletes and experts. Whether you’re looking to improve recovery, performance, or overall wellness, Momentous has you covered. Use code NEURO for 20% off your order: https://www.livemomentous.com/neuro Troscriptions – Unlock your cognitive potential with precision-dosed nootropics developed by medical experts. Whether you need more focus, clarity, or energy, Troscriptions offers innovative solutions. - Get 10% off: https://troscriptions.com/NEURO - https://troscriptions.com/discount/NEUROMAIL?utm_source=affiliate&utm_medium=email&utm_campaign=NeuroMail Timestamps  00:00 Introduction  02:30 Methylene Blue"s Role in Neurotransmitter Regulation  07:54 Mitochondrial Health and Methylene Blue  17:02 Methylene Blue and Modern Health Challenges  25:27 Methylene Blue in Hypobaric and Hyperbaric Environments  29:47 Understanding Hyperbaric Oxygen Therapy  32:27 Methylene Blue: A Mitochondrial Rescue  36:52 Bioavailability of Methylene Blue  42:17 Dosing and Applications of Methylene Blue  47:46 Combining Methylene Blue with Other Treatments  54:02 Conclusion and Further Resources The Neuro Athletics Newsletter Instagram: @louisanicola_ Twitter : @louisanicola_ YouTube: @Louisa Nicola The Neuro Experience Podcast is proud to have hosted: Dr Andrew Huberman, Dr Gabrielle Lyon, Dr Layne Norton, Thomas DeLauer, Shawn Stevenson, Dr. Rocio Salas-Whalen, Saad Alam, Uma Naidoo, Dr. Lanna Cheuck, Angela Lee Pucci, Jillian Turecki, Dr. Jordan Feigenbaum, Dr. Darren Candow, Dr. Sue Varma, Evy Poumpouras, Dr Casey Means, Renee Deehan, Dr Chris Palmer, Dr Charles Brenner, Dr Joe Zundell, Dr Ray Dorsy, Dr Dale Bredeson, Dr. Ben Bikman

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