The Human Upgrade with Dave Asprey

Updated: 01 May 2025 • 1332 episodes
daveasprey.com/category/podcasts

For a decade, Dave Asprey, “the father of biohacking,” elevated what you knew about the capabilities of your mind and body across a thousand episodes of Bulletproof Radio. Now, he’s evolving it even further in his plan to upgrade humanity. You’re invited to expand your knowledge, explore your own performance and embrace possibility with The Human Upgrade™. You’ll meet bright thinkers and radical doers who push the boundaries of science, technology, personal development, and human performance in every way imaginable. You’ll learn from experts around the world who elevate what it means to be human. Every guest you listen to, every topic you learn about, every new idea you discover on this podcast moves you forward. Join The Human Upgrade™ with Dave Asprey on this next evolution to upgrade your mind, body and life. 

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What if a laser could help a child speak for the first time—or reverse an “incurable” brain condition?  In this episode of The Human Upgrade, Dave Asprey talks with Dr. Brandon Crawford, a leading neurotherapist and founder of 528 Innovations, about the emerging science of laser therapy for the brain and body. You’ll l

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What if mitochondria weren’t just energy engines — but conscious beings guiding your survival and evolution?  In this episode, Dave Asprey sits down with Zach Bush, MD, to uncover a radical new science of cellular intelligence. Together, they reveal how your mitochondria, microbiome, and genetic memory do far more than

102 min
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You’ve probably heard of HIIT—but have you heard of “REHIT?”  This isn’t just another workout trend...it’s a new science-backed way to train with maximum efficiency and zero wasted time. If you’re still jogging, you’re wasting hours for minimal results.  In this episode of The Human Upgrade, Dave Asprey sits down with

66 min
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Your bloodwork looks normal. Your doctor says you’re fine. But you still feel exhausted, inflamed, anxious—or worse.  In this episode, Dave Asprey talks with Dr. Daniel Pompa, a leading voice in cellular detox and root-cause healing, to expose the hidden stressors hijacking your energy, hormones, and metabolism—even wh

78 min
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Most people run from stress. The world’s highest performers run toward it.  Sébastien Page manages over $500 billion in global assets. He’s the CIO of one of the world’s largest investment firms, and he wrote The Psychology of Leadership while living under relentless pressure. His secret? He doesn’t avoid stress—he use

80 min
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Your DNA, health data, and digital identity are encrypted, monetized, and weaponized against you.  But what if there was a way to take it back… and hack the system?  In this mind-expanding episode, Dave sits down with two elite hacker-founders—Michael Tiffany, CEO of Fulcra.ai, and Vishakh, founder of Monadic DNA—to ex

90 min
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