Death Clock

This week, Brent speaks with Sir Adrian Bird, the pioneering geneticist whose discoveries on DNA methylation reshaped our understanding of how genes are regulated. Bird explains what DNA methylation actually is and why he's skeptical of popular claims that it determines "biological age" or can be easily hacked to rever

In this episode of Death Clock, Brent speaks with Dr. Nazish Sayed, a Stanford cardiologist and vascular biologist, to cut through the confusion about cholesterol, heart disease, and statins. Dr. Sayed breaks down what LDL, HDL, and ApoB really mean, why high cholesterol is more about your biology than your breakfast,

This week, Brent speaks with Dr. John Buse, a leading endocrinologist at the University of North Carolina and one of the world's foremost experts on diabetes and metabolic health. Dr. Buse unpacks the science behind GLP-1 agonists like Ozempic and Wegovy. He explains their powerful benefits for obesity, diabetes, and h

In this episode of Death Clock, Brent speaks with Dr. Matthew Taylor, the director of the Brain Nutrition Lab at the University of Kansas Medical Center, to break down everything you need to know about the ketogenic diet. They talk about what it is, how it works, and what science actually says about its benefits. Dr. T

In this episode, Brent speaks with Dr. Arthur Agatston, world-renowned cardiologist, creator of the South Beach Diet, and the pioneer behind the Agatston Score, better known as the calcium score. Dr. Agatston explains how this simple, low-cost CT scan can reveal hidden plaque in the arteries long before symptoms arise,

This week's guest is Dr. Yaakov Stern, Florence Irving Professor of Neuropsychology at Columbia University Medical Center. Dr. Stern and Brent discuss the science and lived reality of Alzheimer's disease and dementia. They talk about what distinguishes normal cognitive aging from dementia, how biomarkers like amyloid a