
Mind & Matter
Whether food, drugs or ideas, what you consume influences who you become. Learn directly from the best scientists & thinkers alive today about how your mind-body reacts to what you feed it. The weekly M&M podcast features conversations with the most interesting scientists, thinkers, and technology entrepreneurs alive today. Not medical advice. At M&M, we are interested in trying to figure out how things work, not affirming our existing beliefs. We prefer consulting primary rather than secondary sources and independent rather than institutional voices. If we encounter uncomfortable truths or the evidence suggests unfashionable ideas may be valid, so be it. As the host, my aim is to help you better understand how the body & mind work by curating & synthesizing information in a way that yields science-based insights that you can choose to use or disregard in your own life. Taking ownership of your health starts with taking ownership of your information diet. I am motivated to connect the dots and distill general principles from what I learn, preferring to ask questions and play devil’s advocate to debating or incessantly pushing my own viewpoint. My beliefs: Taking ownership of your health starts with taking ownership of your information diet.All knowledge is provisional and we must work hard to prevent ourselves from becoming attached to our favorite ideas & preferred conclusions.Wisdom comes from an iterative, trial-and-error process of learning and unlearning. Letting go of pre-conceived notions can be painful, but pain is information. Sometimes modern discoveries teach us we must unlearn received wisdom. Other times, modern information overload & historical chauvinism cause us to forget ancient wisdom which stills applies. The framework for learning that I embody is inspired by three Ancient Greek maxims inscribed in the Temple of Apollo at Delphi: “Γνῶθι σεαυτόν” (Know thyself)“Μηδὲν ἄγαν” (Nothing in excess)“Ἐγγύα πάρα δ Ἄτα” (Certainty brings insanity)
Show episodes
Send us a text Cellular clean up by immune cells and how early-life fructose exposure leads to neurodevelopmental problems. Episode Summary: Dr. Justin Perry talks about the body"s constant cellular turnover—about 3 million cells die per second in adults (double in children and women)—handled by phagocytes like macroph
Send us a text The potential link between acetaminophen (Tylenol) and autism, with a surprise phone call from RFK partway through. Episode Summary: Dr. William Parker talks about autism spectrum disorder (ASD), its rising prevalence since the 1980s, and the controversial hypothesis that acetaminophen exposure in suscep

Cholesterol: Immune Benefits, Heart Health, Statins & Research Malpractice | Uffe Ravnskov | 247
Send us a text Wide release date: August 25, 2025 Episode Summary: Dr. Uffe Ravnskov talks about his decades-long career challenging the idea that high cholesterol causes heart disease, discussing LDL"s protective role in the immune system by binding to bacteria, the harms and biases in statin research influenced by ph
Send us a text The appendix"s hidden role and how "good" parasites like helminths shape immune health. Episode Summary: Dr. William Parker discusses gut anatomy, the appendix"s role in harboring beneficial bacterial biofilms and immune tissue, and how modern hygiene depletes helminths (intestinal worms), causing immune

Cannabinoid System: Metabolism, Evolution & Energy Storage | Giovanni Marsicano | 245
Send us a text What is the core evolved function of the endocannabinoid system? Episode Summary: Dr. Giovanni Marsicano is a neuroscientist based in Bordeaux, France, where he leads a research group at INSERM focusing on the endocannabinoid system. About the guest: Giovanni Marsicano, PhD discusses the endocannabinoid

Seed Oils & Heart Disease: Oxidized LDL, Cholesterol, Fat & Cardiology | Tucker Goodrich | 244
Send us a text Overview and alternative interpretation to the mainstream view on how dietary fat and cholesterol relate to cardiovascular disease. Episode Summary: Tucker Goodrich is an engineer by training who has become a prominent independent researcher and blogger on nutrition and metabolic health, focusing on the