Literally! With Rob Lowe

Updated: 22 May 2025 • 271 episodes
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This is literally a podcast where people I love, admire, and know well will be in a safe space to really let their hair down (assuming they have any). I will cover the thoughtful to the extremely random. So join me and my guests from the world of movies, TV, sports, music, and culture for fun, wide-ranging, free-wheeling conversations. Subscribe to SiriusXM Podcasts+ to listen to new episodes of Literally with Rob Lowe ad-free. Start a free trial now on Apple Podcasts or by visiting siriusxm.com/podcastsplus.

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Rob and Ike are the biggest Kate Hudson fans! Actor Ike Barinholtz (The Mindy Project, The Studio, Running Point) joins Rob Lowe to talk about their mutual friends Kate Hudson and Amy Poehler, the time Ike ate the coconut cake Tom Cruise gifted to Mindy Kaling, Rob’s look-a-like in the Lakers organization, doing improv

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Penn and Rob wish they were invited to "We Are the World!" Magician, television presenter, and author Penn Jillette (of Penn & Teller) joins Rob Lowe to discuss his surprising favorite magic trick, the genius of Bob Dylan, 50 years of “Penn & Teller,” and his new novel. Make sure to subscribe to the show on YouTube at

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Kelsey Grammer returns to "Literally” for a moving episode. The "Frasier" and "Cheers" star joins Rob Lowe to discuss his deeply cathartic new book, "Karen: A Brother Remembers," the tragic loss of his sister, his return to the world of "X-Men" and Marvel, why he still finds joy in acting, and much more.   Make sure to

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It’s always outrageous when Rob and Chelsea Handler get together! Comedian, writer, and host of the “Dear Chelsea” podcast Chelsea Handler joins Rob Lowe to discuss their perspectives on aging, the ski season, what she’s looking for in an “international boyfriend,” Rob’s early days of sobriety, and much more. Make sure

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Filmmaker Gavin O'Connor joins Rob Lowe to discuss casting Kurt Russell in the classic hockey film "Miracle," his collaborations with Ben Affleck, working with Keri Russell on "The Americans," the genius of Paul Newman, favorite Broadway performances, his new film "The Accountant 2," and much more. Make sure to subscri

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17 Apr 2025 • EN

Jason Isaacs: TV Dad

Jason Isaacs and Rob Lowe are fighting over Patrick Schwarzenegger! The “White Lotus" and "Harry Potter" actor joins Rob Lowe to discuss his brushes with injury on the set of “White Lotus,” the Duke University controversy, his belief in ghosts, TV kids vs. your real-life kids, and much more. Make sure to subscribe to t

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