JAMA Clinical Reviews

Early-onset gastrointestinal cancers, typically defined as occurring in patients younger than age 50, are increasing worldwide. A recent JAMA Review summarizes current data on early-onset colorectal, pancreatic, and esophagogastric cancers. Coauthor Kimmie Ng, MD, MPH, of Dana-Farber Cancer Institute joins JAMA Deputy

Approximately 40% of men older than 50 have urinary frequency or urgency that affects their quality of life. Author John T. Wei, MD, MS, of the University of Michigan Department of Urology and JAMA Deputy Editor Mary M. McDermott, MD, discuss diagnosis and management of these symptoms in older men. Related Content: Low

In the 25 years since its emergence in the US, West Nile virus has become the leading cause of domestic mosquito-borne disease. It causes approximately 1300 neuroinvasive disease cases and 130 deaths annually in the US. Coauthor Carolyn Gould, MD, of the CDC joins JAMA Senior Editor Karen Lasser, MD, to discuss the rev

Worldwide, 1 in 3 women and 1 in 5 men older than 50 years experience osteoporotic fractures in their lifetime. Author Suzanne N. Morin, MD, MSc, of McGill University and JAMA Deputy Editor Mary M. McDermott, MD, discuss the diagnosis and management of osteoporosis. Related Content: Osteoporosis

Which tests can be used to diagnose type 2 diabetes? When should injectable medications for type 2 diabetes be started? These are just some of the questions clinicians may have when diagnosing and treating type 2 diabetes in adults. Author Rita Kalyani, MD, MHS, of Johns Hopkins University School of Medicine, discusses

Adrenal insufficiency is a syndrome of cortisol deficiency. A recent JAMA Review summarizes the pathophysiology, diagnosis, and treatment of adrenal insufficiency and adrenal crisis. JAMA Associate Editor David Simel, MD, MHS, discusses this and more with author Anand Vaidya, MD, MMSc. Related Content: Adrenal Insuffic