Probably Science

Updated: 20 Oct 2025 • 595 episodes
probablyscience.com

Professional comedians with so-so STEM pedigrees take you through this week in science. Incompetently. Featuring hosts Matt Kirshen, Andy Wood (and sometimes Jesse Case or Brooks Wheelan) along with a rotating cast of special guests from the worlds of comedy and science.

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20 Oct 2025 • EN

Episode 582 - Jen Kober

Comedian/actor Jen Kober (@jenkober) joins Andy, Jesse and Matt to talk about comedy in Louisiana, Oktoberfest, buxom wenches, the connection between fish buttholes and fingers, a koala chlamydia vaccine, Jesse's newfound raccoon fame, light-powered gears that fit inside a strand of hair and Jen's membership in the Sta

71 min
00:00
01:11:56
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NASA astrophysicist and JPL Exoplanet Science Ambassador Anjali Tripathi joins Andy, Jesse and Matt to talk about exoplanets and the different ways of finding them including radial velocity, transits and gravitational microlensing, the challenges of studying planetary atmospheres, why telescopes are built in deserts or

80 min
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01:20:46
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Comedian Michelle Murphy (@meeshoffleash) joins Andy, Matt and Jesse to talk about playing tennis for Grinnell, the Enhanced Games, celebrities trying their hands at winter sports, Jesse's accidental mermaid book purchase and the Dr. Seuss book he was aiming for, Burning Man missionaries, LSD to fight anxiety and surpr

81 min
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17 Sep 2025 • EN

Episode 579 - Ken Reid

Comedian Ken Reid (@kennethwreid) joins Jesse, Matt and Andy to talk about growing up a child of television, mud wrestling, Ken's podcast TV Guidance Counselor, an HIV prevention breakthrough, the insanity of Movie 43, the human washing machine no one asked for, blasting plastic waste with a plasma torch, Doja Cat's no

75 min
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01:15:54
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Comedian Ryan O'Flanagan (@ryanoflan) joins Matt, Jesse and Andy to talk about Ryan and Andy's chance encounter in a bar in Leadville, Married With Children tattoos, neanderthals and homo sapiens interbreeding, a novel telescope shape to help search for exoplanets, an insane impression of a neanderthal voice and Ryan's

71 min
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01:11:38
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29 Aug 2025 • EN

Episode 577 - Myq Kaplan

Comedian Myq Kaplan (@myqkaplan) returns to the show to talk to Andy, Jesse and Matt about growing out his eyebrows during the pandemic, babies distinguishing Ps from Bs, linguistics, sign language variations, standups aping Shane Gillis, the Mr. Beast voice, birds' preference for crapping in the air, strong link versu

71 min
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01:11:37
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