Out of Patients with Matthew Zachary

Updated: 16 Oct 2025 • 454 episodes
art19.com/shows/outofpatients

Out of Patients with Matthew Zachary is the longest-running, independent healthcare podcast.  Since 2007, Matthew’s been calling out the hypocrisy, hubris, and hostage-taking baked into American healthcare—with a mic in one hand and a middle finger in the other.  What started as a pirate radio rebellion is now the most trusted, notorious, and unfiltered show in the game. Patients love it. Industry listens. And anyone who’s ever been gaslit by the system knows exactly where to turn to nod their heads in shared rage. Every episode delivers unsanitized stories, dark humor, policy takedowns, and angsty GenX truth bombs—told by the people living it, not spinning it. It’s the show you love about the healthcare you hate.

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Dr. Nikki Maphis didn’t just lose a grant. She lost a lifeline. An early-career Alzheimer’s researcher driven by her grandmother’s diagnosis, Nikki poured years into her work—only to watch it vanish when the NIH’s MOSAIC program got axed overnight. Her application wasn’t rejected. It was deleted. No feedback. No score.

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Carla Tardif has spent 17 years as the CEO of Family Reach, a nonprofit that shouldn’t have to exist but absolutely does—because in America, cancer comes with a price tag your insurance doesn’t cover. We talk about shame, fear, burnout, Wegmans, Syracuse, celebrity telethons, and the godforsaken reality of choosing bet

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Jennifer J. Brown is a scientist, a writer, and a mother who never got the luxury of separating those roles. Her memoir When the Baby Is Not OK: Hopes & Genes is a punch to the gut of polite society and a medical system that expects parents to smile through trauma. She wrote it because she had to. Because the people wh

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This episode of Standard Deviation features Oliver Bogler in conversation with Dr Na Zhao, a cancer biologist caught in the crossfire of science, politics, and survival. Na’s life reads like a brutal lab experiment in persistence. She grew up in China, lost her mother and aunt to breast cancer before she turned twelve,

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Katie Henry has seen some things. From nonprofit bootstraps to Big Pharma boardrooms, she’s been inside the machine—and still believes we can fix it. We go deep on her winding road from folding sweaters at J.Crew to launching a vibrator-based advocacy campaign that accidentally changed the sexual health narrative in br

43 min
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What happens when you hand a mic to the most extroverted, uncensored Gen Z career coach in New York? You get Olivia Battinelli—adjunct professor, student advisor, mentor, speaker, and unfiltered truth-teller on everything from invisible illness to resume crimes. We talked about growing up Jewish-Italian in Westchester,

42 min
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