Depresh Mode with John Moe

Updated: 26 Nov 2025 • 258 episodes
maximumfun.org/podcasts/depresh-mode

Join host John Moe (The Hilarious World of Depression) for honest, relatable, and, yes, sometimes funny conversations about mental health. Hear from comedians, musicians, authors, actors, and other top names in entertainment and the arts about living with depression, anxiety, and many other common disorders. Find out what they’ve done to address it, what worked, and what didn’t. Depresh Mode also features useful insights on mental health issues with experts in the field. It’s honest talk from people who have been there and know their stuff. No shame, no stigma, and more laughs than you might expect.

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Yes, the holidays are upon us. Getting together with family can be a wonderful, loving experience. It can also be a lot. There can be old grudges, chafing at family roles, the specter of politics might play in. We’re here to help. In This Family is a podcast produced by our host, John Moe, for Nexus Family Healing, a m

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Cotard’s delusion, also known as Cotard’s syndrome, is an extremely rare condition where the patient believes that they are actually dead. For the bestselling author Esmé Weijun Wang, Cotard’s came along after she had already been traveling a difficult road that involved schizoaffective disorder along with a host of ot

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You may find the charges in this episode jarring: depression is not the result of a chemical imbalance, SSRIs aren’t necessarily antidepressants, and the term you use for your mental health condition isn’t scientifically valid. Sarah Fay, author of Pathological: The True Story of Six Misdiagnoses says it’s dangerous to

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Over half the employees at the Substance Abuse and Mental Health Services Administration (SAMHSA) who were there in January are now gone, include 12 of the 17 senior leaders. SAMHSA is in charge of distributing and administering mental health programs around the country and the cuts to both staffing and to the programs

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When we went looking for information on the condition known as seasonal affective disorder, or SAD, one of the first things we noticed was that some people aren’t even calling it that anymore. The website for the National Alliance on Mental Illness (NAMI), for instance, uses the term “major depressive disorder with a s

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It’s a question we ask a lot on this show: do you have a mental health problem or is the problem actually rooted in the world you live in? Psychologist Dr. Jonathan Mathias Lassiter says contemporary society lives under three different assumptions: there’s not enough to go around, kill or be killed, and us versus them

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