Depresh Mode with John Moe

Updated: 20 Oct 2025 • 252 episodes
maximumfun.org/podcasts/depresh-mode

Join host John Moe (The Hilarious World of Depression) for honest, relatable, and, yes, sometimes funny conversations about mental health. Hear from comedians, musicians, authors, actors, and other top names in entertainment and the arts about living with depression, anxiety, and many other common disorders. Find out what they’ve done to address it, what worked, and what didn’t. Depresh Mode also features useful insights on mental health issues with experts in the field. It’s honest talk from people who have been there and know their stuff. No shame, no stigma, and more laughs than you might expect.

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Robert F. Kennedy, Jr., the Secretary of Health and Human Services, clearly does not like SSRIs (selective serotonin reuptake inhibitors), the most popular form of antidepressant on the market. They’re used by millions of Americans on a daily basis. He has tried to tie SSRIs to school shooters despite a lack of evidenc

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During the violent Charlottesville protests of 2017, journalist and author P.E. Moskowitz was only a few feet away when Heather Heyer was killed by an attacking motorist. 16 years earlier, P.E. was in middle school Spanish class a couple blocks from the World Trade Center during the 9/11 attacks. The trauma contributed

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If you are one of the many subscribers to the Peloton exercise/media network, you may already be familiar with Kendall Toole. For many years, she was one of the stars of Peloton, exhorting users to push themselves harder, sweat more, and pursue their goals. In those cases, Kendall was positive, cheerful, always with a

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At age 59, Anne Abel had never been to a concert. Ever. Music wasn’t part of her upbringing, although emotional abuse and belittlement from her parents absolutely were. Reluctantly agreeing to join her son and daughter-in-law to see Bruce Springsteen, Anne’s mind was absolutely blown by the energy and generosity of the

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While the acclaimed musician Emma Swift had experienced painful periods of depression in the past, fed by grief or the first Trump presidency, her psychotic break and mental breakdown in 2023 was new territory. She lost touch with reality, believing that her electronic devices had been hacked, that she was being follow

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Are ChatGPT and other AI chatbots inducing psychosis? Or exacerbating it? Are people being hospitalized or even killed because the bots seem too human, too understanding, too lifelike? To be clear, the bots are not human. They are software. But they are so convincingly programmed to speak like people that users, especi

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