Web3 with Sam Kamani

Updated: 01 Aug 2025 • 280 episodes
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"Web 3.0 with Sam Kamani" is all about Web 3 and how it is going to change the world. If you are interested in learning more about the 4th Industrial revolution then this podcast is for you. Web 3.0 or Web 3 is often hailed as the technology that will usher in the 4th industrial revolution. This revolution is going to affect every industry, business, government and person on this planet. Web 3.0 is a collection of technologies that are going to change how we collaborate with each other and interact with our environment. Let's uncover the opportunities and risks of the new version of Web.

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Jan, founder of OpenMind, joins Sam to discuss how they're building a memory layer for AI agents in Web3. They cover the limitations of stateless agents, OpenMind’s modular memory architecture, and how developers can build “smart, sovereign agents” that persist across time, dApps, and chains. Jan also shares insights o

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Simon Davis, founder of GOAT Gaming and Mighty Bear Games, joins Sam to unpack how they’re using Telegram, AI agents, and meme culture to scale Web3-native games. He breaks down their AI-powered assistant “Amy,” the technical challenges of building engaging agents, and how GOAT reached 6M+ users with Telegram-first dis

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James Quinn Kumar from Binance ANZ joins Sam to explore how Binance reached over 280 million users in just 8 years. He shares the lessons from Facebook and TikTok that helped Binance thrive in B2C, the role of liquidity in institutional adoption, and how Gen Z sees Bitcoin as a new path to wealth in a world of rising p

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In this episode, Charlie, co-founder of Bitlayer, shares how they are building a Bitcoin rollup and trust-minimized BVM bridge to unlock BTC liquidity for DeFi while maintaining Bitcoin-level security. Backed by Franklin Templeton and top mining pools like F2Pool, Bitlayer is enabling yield-bearing BTC (YBTC), partners

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What happens when an emerging‑markets banker, lifelong Reddit degen, and early Ethereum believer builds a global crypto fund focused on AI? Meet Matthew “Matty” Graham, Managing Partner at Ryze Labs. Matty shares how a pizza post pulled him into Bitcoin, why the Ethereum whitepaper was his “drop everything” moment, and

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In this episode, COTI Network CEO Shahaf Bar-Geffen joins Sam to unpack why privacy + scalability are the two missing pillars holding crypto back from mass, institutional adoption. Shahaf recounts COTI’s journey from 2017 payment rails to today’s garbled-circuit EVM, explains “privacy on demand” for any chain, and reve

30 min
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