Vital Signs with Jacob Effron and Nikhil Krishnan

Updated: 01 May 2025 • 58 episodes
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On Vital Signs, Jacob Effron and Nikhil Krishnan dig into cutting-edge trends in healthtech and the people shaping them. Every two weeks they’ll explore a new sub-sector and trend with policy leaders, startup founders and industry executives. Subscribe now to make sure you don’t miss any of it!

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Jacob and Nikhil sit down with Otto Sipe. Otto is the CEO and Co-Founder of Photon Health, which enables patients to select their own pharmacies with price and inventory transparency. The company has raised over $16 million from investors including Flare Capital Partners and Notation Capital. They discuss where pharmac

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Jacob and Nikhil sit down with Dr. Rushika Fernandopulle. Rushika is the former CEO and Co-Founder of Iora Health, a primary care provider centered around value-based care and Medicare that One Medical acquired for $2.1 billion. They discuss why we’re still in the second inning of value-based care, intersections of tec

39 min
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Jacob and Nikhil sit down with Frank Wu, the Co-Founder and CEO of Taro Health. Taro Health is a health insurance plan currently live in Maine and Oklahoma that offers unlimited primary care and mental health visits. The company has raised over $18m from investors like Hummingbird Ventures, Quiet Capital, and FPV Ventu

42 min
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Jacob sits down with Erik Wexler, the President and CEO of Providence. Providence is a non-profit, faith-based health system with 51 hospitals and 1,000 clinics across seven states. They discuss how to think about new AI opportunities with discipline, the value of health system partnerships, programs to support health

35 min
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Jacob and Nikhil sit down with Daniel Perez, the Co-Founder and CEO of Hinge Health. Hinge Health is a digital clinic for patients with joint and muscle pain, having raised $800M+ from investors like Coatue and Tiger Global. They discuss Hinge Health’s strategy for selling to employers, how digital health solutions can

45 min
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Jacob sits down with Hemant Taneja, the CEO & Managing Director of General Catalyst. GC is one of the world’s largest venture capital firms, most recently raising an $8B fund in 2024. The firm has invested in companies like Livongo, Cityblock Health, and Hippocratic AI. They discuss the possibility of a $100B healthcar

42 min
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