Heart of the Matter

Updated: 18 Nov 2025 • 81 episodes
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Heart of the Matter with Elizabeth Vargas is a production from Partnership to End Addiction. Heart of the Matter is an interview series that gives guests the opportunity to share their personal, candid stories about addiction. This podcast offers a space to open up about addiction, substance use and mental health, to share the ways in which people are shifting their narrative – in their own relationships and across communities – to support the cause of ending addiction in our country. Worried about your child or loved one? Partnership to End Addiction's helpline is here for you and anyone else playing a supportive role in the life of a person struggling with substance use. Get one on one support by texting JOIN to 55753 or visit https://helphope.net/3koi6Kh to learn more. Message and data rates may apply. Message frequency varies. Text HELP for help or STOP to opt out. Editor’s Note: The views and opinions expressed on Heart of the Matter are those of the podcast participants and do not necessarily reflect the official policy or position of Partnership to End Addiction. We are also mindful that some of the personal stories feature the word “addict” and other terms from the following link. We respect and understand those who choose to use certain terms to express themselves. However, we strive to use language that’s health-oriented, accurately reflects science, promotes evidence-based treatment and demonstrates respect and compassion. https://drugfree.org/article/shouldnt-use-word-addict/

Show episodes

Lara Love Hardin discusses her journey from suburban soccer mom hiding a heroin addiction to bestselling author. As a result of stealing money and credit cards to fund her addiction, The Many Lives of Mama Love: A Memoir of Lying, Stealing, Writing, and Healing author shares how jail helped her rediscover writing and i

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Jim Sonefeld, drummer for Hootie & the Blowfish, shares his powerful journey from concert tours fueled by alcohol to finding recovery at age 40. He opens up about hiding his drinking behind the rock-and-roll lifestyle, the intervention that came from his 4-year-old daughter, and how he"s rebuilt his life through recove

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After losing one son to overdose and watching another struggle with lifelong schizophrenia, neuroscientist Dr. Kristen Gilliland reveals what she wishes she"d known about today"s ultra-potent marijuana and the developing brain. She breaks down the science of how THC hijacks the adolescent brain"s critical development p

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William Perry shares his powerful journey from childhood trauma and opioid addiction to a 10-year prison sentence, and ultimately to co-founding This Must Be the Place, an organization that combines music, arts, and harm reduction. Now in recovery, Perry and his team distribute naloxone kits at concerts and festivals a

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Can GLP-1 medications like Ozempic help treat addiction? Elizabeth Vargas talks with Pat Aussem, Vice President of Consumer Clinical Content Development at Partnership to End Addiction, about the ongoing clinical trials and the science behind how these drugs work on the brain"s reward system. From promising early resul

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Season 7 of Heart of the Matter kicks off with country pop star Walker Hayes, whose Grammy-nominated hit "Fancy Like" catapulted him to fame. Walker opens up about his journey from drinking at 13 to finding recovery at 35. He discusses his deeply personal 2024 EP "Sober Thoughts," and shares a raw, honest conversation

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