49ers Talk: A San Francisco 49ers Podcast

Matt Maiocco shares the 49ers’ injury update before sitting down with Greg Papa to recap San Francisco’s thrilling 26-23 overtime win over the Los Angeles Rams on Thursday night at SoFi Stadium and discuss how the victory can set the tone for the rest of the season. -- (2:25) Matt shares 49ers’ postgame injury updates

An injured 49ers squad defied the odds and dug deep for a 26-23 overtime win over the Los Angeles Rams on Thursday at SoFi Stadium. Backup quarterback Mac Jones delivered his third win in three starts despite laboring through pain all game. Kyle Shanahan managed a very limited and at times inexperienced San Francisco s

John Lynch joins Matt Maiocco to break down the 49ers' first four games of the 2025 NFL season, from how San Francisco's rash of injuries affect his front-office priorities to some of the more positive on-field developments during their resilient start. Jennifer Lee Chan also joins Matt to preview the 49ers' Week 5 mat

An afternoon of errors resulted in the 49ers' first loss of the 2025 NFL season Sunday against the Jacksonville Jaguars. Despite a second-half comeback attempt, San Francisco couldn't overcome its four turnovers. Brock Purdy's looked shaky in his return from injury after missing the last two weeks with turf toe. Matt M

Matt Maiocco speaks with 49ers coach Kyle Shanahan about San Francisco's Week 4 matchup vs. the Jacksonville Jaguars and also discusses Nick Bosa’s season-ending ACL injury. Greg Papa joins Matt to discuss defensive coordinator Robert Saleh’s comments about the Jaguars’ signal stealing and Brock Purdy returning from in

Despite their undefeated status, the Nick Bosa-less 49ers must persevere as the Jacksonville Jaguars visit Levi's Stadium this Sunday. Matt Maiocco and Jennifer Lee Chan discuss who will step up in Bosa's place and how San Francisco can adapt in other injury-bitten position groups. Plus, Matt and Jennifer detail how De